Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments

Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments

Infectious diseases are a global public health problem; they are among the leading causes of death worldwide and consume a significant amount of resources. Fungi are the most common pathogens in humans and animals. Fungal infections incidence has increased more than 200%. Currently, antifungal agent...

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Główni autorzy: Pérez Arriola, Yarithza, Vázquez Muñoz, Roberto, Bogdanchikova, Nina, Huerta Saquero, Alejandro
Format: Online
Język:spa
eng
Wydane: Universidad Autónoma de Baja California 2018
Dostęp online:https://recit.uabc.mx/index.php/revista/article/view/51
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spelling recit-article-512022-10-12T23:18:02Z Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments Efecto sobre la actividad antimicrobiana de los agentes antimicóticos: tratamientos combinados con nanopartículas de plata Pérez Arriola, Yarithza Vázquez Muñoz, Roberto Bogdanchikova, Nina Huerta Saquero, Alejandro Nanoantibiotics Silver Nanoparticles Infectious Diseases Synergy Candida albicans. Nanoantibióticos Nanopartículas de plata Enfermedades infecciosas Sinergia Candida albicans. Infectious diseases are a global public health problem; they are among the leading causes of death worldwide and consume a significant amount of resources. Fungi are the most common pathogens in humans and animals. Fungal infections incidence has increased more than 200%. Currently, antifungal agents are used for combating fungal infections, but there are many problems associated with their use, such as the emergence of resistant organisms, as well as the complexity related to the development of new antibiotics. In that sense, silver nanoparticles have proven to be an alternative solution to fight fungal infections due their capacity to inhibit fungal growth. In this work, we studied the antimicrobial activity of silver nanoparticles (AgNPs), antifungal agents (Amphotericin B and Fluconazole) and combinations of both, AgNPs-antifungals over the pathogenic dimorphic yeast Candida albicans. The antimicrobial tests were performed according to the CLSI ́s M27-A3 protocols. Combined AgNPs-antifungal treatments showed a different effect on antimicrobial activity. We found a synergistic effect of specific combined treatment, whereas antagonistic effect was observed with other combination. En este trabajo se plantea la importancia de la estrategia en la organización como factor detonante para los procesos de innovación y competitividad empresarial. ¿Cuáles son las estrategias de las empresas para lograr innovación organizacional? “La pregunta fundamental en el campo de la dirección estratégica es cómo las firmas consiguen y sostienen la ventaja competitiva”. La investigación se orienta hacia factores de innovación organización como son la productividad y la flexibilidad laboral, explorando en las organizaciones la relación entre la capacidad tecnológica y los sistemas de información como variables de la productividad. Así mismo se propone un modelo matemático para estimar la productividad en base a las variables de capacidad tecnológica y los sistemas de información. Universidad Autónoma de Baja California 2018-01-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Research article Articulo de Investigación application/pdf text/html application/xml https://recit.uabc.mx/index.php/revista/article/view/51 10.37636/recit.v126971 REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 1 No. 2 (2018): October-December; 69-71 REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 1 Núm. 2 (2018): Octubre-Diciembre; 69-71 2594-1925 spa eng https://recit.uabc.mx/index.php/revista/article/view/51/94 https://recit.uabc.mx/index.php/revista/article/view/51/117 https://recit.uabc.mx/index.php/revista/article/view/51/126 Copyright (c) 2018 ​Pérez Arriola Yarithza, Vázquez Muñoz Roberto, Bogdanchikova Nina, Huerta Saquero Alejandro http://creativecommons.org/licenses/by/4.0
institution RECIT
collection OJS
language spa
eng
format Online
author Pérez Arriola, Yarithza
Vázquez Muñoz, Roberto
Bogdanchikova, Nina
Huerta Saquero, Alejandro
spellingShingle Pérez Arriola, Yarithza
Vázquez Muñoz, Roberto
Bogdanchikova, Nina
Huerta Saquero, Alejandro
Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
author_facet Pérez Arriola, Yarithza
Vázquez Muñoz, Roberto
Bogdanchikova, Nina
Huerta Saquero, Alejandro
author_sort Pérez Arriola, Yarithza
title Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
title_short Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
title_full Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
title_fullStr Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
title_full_unstemmed Effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
title_sort effect on antimicrobial activity of antifungal agents-silver nanoparticles combined treatments
description Infectious diseases are a global public health problem; they are among the leading causes of death worldwide and consume a significant amount of resources. Fungi are the most common pathogens in humans and animals. Fungal infections incidence has increased more than 200%. Currently, antifungal agents are used for combating fungal infections, but there are many problems associated with their use, such as the emergence of resistant organisms, as well as the complexity related to the development of new antibiotics. In that sense, silver nanoparticles have proven to be an alternative solution to fight fungal infections due their capacity to inhibit fungal growth. In this work, we studied the antimicrobial activity of silver nanoparticles (AgNPs), antifungal agents (Amphotericin B and Fluconazole) and combinations of both, AgNPs-antifungals over the pathogenic dimorphic yeast Candida albicans. The antimicrobial tests were performed according to the CLSI ́s M27-A3 protocols. Combined AgNPs-antifungal treatments showed a different effect on antimicrobial activity. We found a synergistic effect of specific combined treatment, whereas antagonistic effect was observed with other combination.
publisher Universidad Autónoma de Baja California
publishDate 2018
url https://recit.uabc.mx/index.php/revista/article/view/51
_version_ 1792095366475153408

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