Diabetic foot ulcers treatment with silver nanoparticles

Diabetic foot ulcers treatment with silver nanoparticles

Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedic...

Fuld beskrivelse

Guardado en:
Bibliografiske detaljer
Autores principales: Almonaci Hernández, Cesar Alejandro, Cabrera Torres, Isis Marion, López-Acevedo, Rosangela, Juárez-Moreno, Karla Oyuki, Castañeda-Juárez, Martin E., Almanza-Reyes, Horacio, Pestryakov, Alexey, Bogdanchikova, Nina
Format: Online
Sprog:eng
Udgivet: Universidad Autónoma de Baja California 2019
Online adgang:https://recit.uabc.mx/index.php/revista/article/view/55
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
id recit-article-55
record_format ojs
spelling recit-article-552022-10-13T17:15:05Z Diabetic foot ulcers treatment with silver nanoparticles Tratamiento de las úlceras del pie diabético con nanopartículas de plata Almonaci Hernández, Cesar Alejandro Cabrera Torres, Isis Marion López-Acevedo, Rosangela Juárez-Moreno, Karla Oyuki Castañeda-Juárez, Martin E. Almanza-Reyes, Horacio Pestryakov, Alexey Bogdanchikova, Nina Diabetic Foot Ulcers Diabetes Mellitus Silver Nanoparticles Nanomedicine Chronic Ulcers. Red Internacional de Bionanotecnología Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedicine. Herein, we present the usage of AgNPs for the treatment of diabetic foot ulcers with a stage II in Wagner classification. In addition to conventional antibiotic treatment, the ulcers were treated with topical administration of AgNPs at a concentration of 1.2 mg/ml of metallic silver. The results showed a significant improvement in the evolution of the ulcers, where the edges of the lesion were effectively approached, granulation tissue being observed, edema decreased and fibrin plaques. These results form the basis for further studies on the use of AgNPs for the treatment of chronic ulcers of different origins. Las úlceras del pie diabético son altamente susceptibles a infecciones microbianas y son la principal causa de hospitalización y amputación de extremidades inferiores en pacientes diabéticos. Debido a sus propiedades antimicrobianas y anti-inflamatorias, las nanopartículas de plata (AgNPs) son el nanomaterial más utilizado en biomedicina. En este trabajo presentamos el uso de AgNPs para el tratamiento de úlceras de pie diabético grado II de la clasificación de Wagner. Además del tratamiento con antibióticos convencionales, las úlceras fueron tratadas mediante la administración tópica de AgNPs a una concentración de 1.2 mg/mL de plata metálica. Los resultados obtenidos, revelan una mejora significativa en la evolución de las úlceras, en donde los bordes de la lesión se acercaron de manera efectiva, observándose tejido de granulación, disminución del edema y placas de fibrina. Estos resultados constituyen la base para nuevos estudios sobre el uso de AgNPs para el tratamiento de úlceras crónicas de diferentes orígenes. Universidad Autónoma de Baja California 2019-01-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Research article Articulo de Investigación application/pdf text/html application/xml https://recit.uabc.mx/index.php/revista/article/view/55 10.37636/recit.v212025 REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 2 No. 1 (2019): January-March; 20-25 REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 2 Núm. 1 (2019): Enero-Marzo; 20-25 2594-1925 eng https://recit.uabc.mx/index.php/revista/article/view/55/98 https://recit.uabc.mx/index.php/revista/article/view/55/106 https://recit.uabc.mx/index.php/revista/article/view/55/135 Copyright (c) 2019 Almonaci Hernández Cesar Alejandro, Cabrera Torres Isis Marion, López-Acevedo Rosangela, Juárez-Moreno Karla Oyuki, Castañeda-Juárez Martin E., Almanza-Reyes Horacio, Pestryakov Alexey, Bogdanchikova Nina http://creativecommons.org/licenses/by/4.0
institution RECIT
collection OJS
language eng
format Online
author Almonaci Hernández, Cesar Alejandro
Cabrera Torres, Isis Marion
López-Acevedo, Rosangela
Juárez-Moreno, Karla Oyuki
Castañeda-Juárez, Martin E.
Almanza-Reyes, Horacio
Pestryakov, Alexey
Bogdanchikova, Nina
spellingShingle Almonaci Hernández, Cesar Alejandro
Cabrera Torres, Isis Marion
López-Acevedo, Rosangela
Juárez-Moreno, Karla Oyuki
Castañeda-Juárez, Martin E.
Almanza-Reyes, Horacio
Pestryakov, Alexey
Bogdanchikova, Nina
Diabetic foot ulcers treatment with silver nanoparticles
author_facet Almonaci Hernández, Cesar Alejandro
Cabrera Torres, Isis Marion
López-Acevedo, Rosangela
Juárez-Moreno, Karla Oyuki
Castañeda-Juárez, Martin E.
Almanza-Reyes, Horacio
Pestryakov, Alexey
Bogdanchikova, Nina
author_sort Almonaci Hernández, Cesar Alejandro
title Diabetic foot ulcers treatment with silver nanoparticles
title_short Diabetic foot ulcers treatment with silver nanoparticles
title_full Diabetic foot ulcers treatment with silver nanoparticles
title_fullStr Diabetic foot ulcers treatment with silver nanoparticles
title_full_unstemmed Diabetic foot ulcers treatment with silver nanoparticles
title_sort diabetic foot ulcers treatment with silver nanoparticles
description Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedicine. Herein, we present the usage of AgNPs for the treatment of diabetic foot ulcers with a stage II in Wagner classification. In addition to conventional antibiotic treatment, the ulcers were treated with topical administration of AgNPs at a concentration of 1.2 mg/ml of metallic silver. The results showed a significant improvement in the evolution of the ulcers, where the edges of the lesion were effectively approached, granulation tissue being observed, edema decreased and fibrin plaques. These results form the basis for further studies on the use of AgNPs for the treatment of chronic ulcers of different origins.
publisher Universidad Autónoma de Baja California
publishDate 2019
url https://recit.uabc.mx/index.php/revista/article/view/55
_version_ 1792095367382171648

Lignende værker