Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity

Currently, silver nanoparticles (AgNPs) are extensively studied for biomedical applications, but although nanomaterials provide many benefits, recently their comparative toxicity have barely been explored. In the current work, AgNPs toxicity on biological systems of different levels of complexity wa...

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Autores principales:	Vázquez-Muñoz, Roberto, Borrego-Rivero, Belén, Juárez-Moreno, Karla Oyuky, García-García, Maritza Roxana, Mota-Morales, Josué David, Bogdanchikova, Nina, Huerta-Saquero, Alejandro
Format:	info:eu-repo/semantics/article
Sprog:	eng
Udgivet:	Universidad Autónoma de Baja California 2018
Fag:	Silver Nanoparticles Nanotoxicology Biological Systems Complexity Antimicrobial Activity. Nanopartículas de Plata Nanotoxicología Complejidad de Sistemas Biológicos Actividad Antimicrobiana
Online adgang:	https://recit.uabc.mx/index.php/revista/article/view/oba15
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id	repositorioinstitucional-20.500.12930-6983
record_format	dspace
spelling	repositorioinstitucional-20.500.12930-69832023-05-09T14:35:08Z Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity Nanopartículas de plata como nanoantibióticos: Un análisis comparativo de su toxicidad en sistemas biológicos de diferente complejidad Vázquez-Muñoz, Roberto Borrego-Rivero, Belén Juárez-Moreno, Karla Oyuky García-García, Maritza Roxana Mota-Morales, Josué David Bogdanchikova, Nina Huerta-Saquero, Alejandro Silver Nanoparticles Nanotoxicology Biological Systems Complexity Antimicrobial Activity. Nanopartículas de Plata Nanotoxicología Complejidad de Sistemas Biológicos Actividad Antimicrobiana Currently, silver nanoparticles (AgNPs) are extensively studied for biomedical applications, but although nanomaterials provide many benefits, recently their comparative toxicity have barely been explored. In the current work, AgNPs toxicity on biological systems of different levels of complexity was assessed in a comprehensive and comparatively way. The organisms included viruses, bacteria, microalgae, fungi, animal and human cells (including cancer cell lines). We found that growth of biological systems of different taxonomical groups –in vitro, at a cellular level- is inhibited at concentrations of AgNPs within the same order of magnitude (101 μg/ml). Thus, the AgNPs toxicity does not depend on the complexity of the organisms. The fact that cells and virus are inhibited with a concentration of AgNPs within the same order of magnitude could be explained considering that silver affects fundamental structures for cells and virus alike. Actualmente, las nanopartículas de plata (AgNPs) se estudian ampliamente para aplicaciones biomédicas, pero a pesar de que los nanomateriales proporcionan muchos beneficios, recientemente su toxicidad comparativa apenas se ha explorado. En el trabajo actual, la toxicidad de AgNPs en sistemas biológicos de diferentes niveles de complejidad se evaluó de forma exhaustiva y comparativa. Los organismos incluyen virus, bacterias, microalgas, hongos, células animales y humanas (incluidas líneas celulares cancerosas). Encontramos que el crecimiento de los sistemas biológicos de diferentes grupos taxonómicos -in vitro, a nivel celular- se inhibe a concentraciones de AgNP dentro del mismo orden de magnitud (101 μg / ml). Por lo tanto, la toxicidad de AgNPs no depende de la complejidad de los organismos. El hecho de que las células y los virus se inhiban con una concentración de AgNP dentro del mismo orden de magnitud podría explicarse teniendo en cuenta que la plata afecta las estructuras fundamentales de las células y virus por igual. 2018-09-01 2021-06-03T03:52:20Z 2021-06-03T03:52:20Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Research article Artículo de investigación https://recit.uabc.mx/index.php/revista/article/view/oba15 10.37636/recit.v11811 https://hdl.handle.net/20.500.12930/6983 eng https://recit.uabc.mx/index.php/revista/article/view/oba15/8-11 https://recit.uabc.mx/index.php/revista/article/view/oba15/html https://recit.uabc.mx/index.php/revista/article/view/oba15/OBA15 Copyright (c) 2018 Vázquez-Muñoz Roberto, Borrego-Rivero Belén, Juárez-Moreno Karla Oyuky, García-García Maritza Roxana, Mota Morales Josué David, Bogdanchinkova Nina, Huerta-Saquero Alejandro http://creativecommons.org/licenses/by/4.0 application/pdf text/html application/xml Universidad Autónoma de Baja California REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 1 No. 1 (2018); 8-11 REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 1 Núm. 1 (2018); 8-11 2594-1925
institution	Repositorio Institucional
collection	DSpace
language	eng
topic	Silver Nanoparticles Nanotoxicology Biological Systems Complexity Antimicrobial Activity. Nanopartículas de Plata Nanotoxicología Complejidad de Sistemas Biológicos Actividad Antimicrobiana
spellingShingle	Silver Nanoparticles Nanotoxicology Biological Systems Complexity Antimicrobial Activity. Nanopartículas de Plata Nanotoxicología Complejidad de Sistemas Biológicos Actividad Antimicrobiana Vázquez-Muñoz, Roberto Borrego-Rivero, Belén Juárez-Moreno, Karla Oyuky García-García, Maritza Roxana Mota-Morales, Josué David Bogdanchikova, Nina Huerta-Saquero, Alejandro Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
description	Currently, silver nanoparticles (AgNPs) are extensively studied for biomedical applications, but although nanomaterials provide many benefits, recently their comparative toxicity have barely been explored. In the current work, AgNPs toxicity on biological systems of different levels of complexity was assessed in a comprehensive and comparatively way. The organisms included viruses, bacteria, microalgae, fungi, animal and human cells (including cancer cell lines). We found that growth of biological systems of different taxonomical groups –in vitro, at a cellular level- is inhibited at concentrations of AgNPs within the same order of magnitude (101 μg/ml). Thus, the AgNPs toxicity does not depend on the complexity of the organisms. The fact that cells and virus are inhibited with a concentration of AgNPs within the same order of magnitude could be explained considering that silver affects fundamental structures for cells and virus alike.
format	info:eu-repo/semantics/article
author	Vázquez-Muñoz, Roberto Borrego-Rivero, Belén Juárez-Moreno, Karla Oyuky García-García, Maritza Roxana Mota-Morales, Josué David Bogdanchikova, Nina Huerta-Saquero, Alejandro
author_facet	Vázquez-Muñoz, Roberto Borrego-Rivero, Belén Juárez-Moreno, Karla Oyuky García-García, Maritza Roxana Mota-Morales, Josué David Bogdanchikova, Nina Huerta-Saquero, Alejandro
author_sort	Vázquez-Muñoz, Roberto
title	Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
title_short	Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
title_full	Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
title_fullStr	Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
title_full_unstemmed	Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
title_sort	silver nanoparticles as nanoantibiotics: a comparative analysis of their toxicity on biological systems of different complexity
publisher	Universidad Autónoma de Baja California
publishDate	2018
url	https://recit.uabc.mx/index.php/revista/article/view/oba15
_version_	1792610468312907776

Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity

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