Diabetic foot ulcers treatment with silver nanoparticles

Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedic...

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Huvudupphovsmän:	Almonaci Hernández, Cesar Alejandro, Cabrera Torres, Isis Marion, López-Acevedo, Rosangela, Juárez-Moreno, Karla Oyuki, Castañeda-Juárez, Martin E., Almanza-Reyes, Horacio, Pestryakov, Alexey, Bogdanchikova, Nina
Materialtyp:	info:eu-repo/semantics/article
Språk:	eng
Publicerad:	Universidad Autónoma de Baja California 2019
Ämnen:	Diabetic Foot Ulcers Diabetes Mellitus Silver Nanoparticles Nanomedicine Chronic Ulcers. Red Internacional de Bionanotecnología
Länkar:	https://recit.uabc.mx/index.php/revista/article/view/oba8
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id	repositorioinstitucional-20.500.12930-7012
record_format	dspace
spelling	repositorioinstitucional-20.500.12930-70122023-05-09T14:35:06Z Diabetic foot ulcers treatment with silver nanoparticles Tratamiento de las úlceras del pie diabético con nanopartículas de plata Almonaci Hernández, Cesar Alejandro Cabrera Torres, Isis Marion López-Acevedo, Rosangela Juárez-Moreno, Karla Oyuki Castañeda-Juárez, Martin E. Almanza-Reyes, Horacio Pestryakov, Alexey Bogdanchikova, Nina Diabetic Foot Ulcers Diabetes Mellitus Silver Nanoparticles Nanomedicine Chronic Ulcers. Red Internacional de Bionanotecnología Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedicine. Herein, we present the usage of AgNPs for the treatment of diabetic foot ulcers with a stage II in Wagner classification. In addition to conventional antibiotic treatment, the ulcers were treated with topical administration of AgNPs at a concentration of 1.2 mg/ml of metallic silver. The results showed a significant improvement in the evolution of the ulcers, where the edges of the lesion were effectively approached, granulation tissue being observed, edema decreased and fibrin plaques. These results form the basis for further studies on the use of AgNPs for the treatment of chronic ulcers of different origins. Las úlceras del pie diabético son altamente susceptibles a infecciones microbianas y son la principal causa de hospitalización y amputación de extremidades inferiores en pacientes diabéticos. Debido a sus propiedades antimicrobianas y anti-inflamatorias, las nanopartículas de plata (AgNPs) son el nanomaterial más utilizado en biomedicina. En este trabajo presentamos el uso de AgNPs para el tratamiento de úlceras de pie diabético grado II de la clasificación de Wagner. Además del tratamiento con antibióticos convencionales, las úlceras fueron tratadas mediante la administración tópica de AgNPs a una concentración de 1.2 mg/mL de plata metálica. Los resultados obtenidos, revelan una mejora significativa en la evolución de las úlceras, en donde los bordes de la lesión se acercaron de manera efectiva, observándose tejido de granulación, disminución del edema y placas de fibrina. Estos resultados constituyen la base para nuevos estudios sobre el uso de AgNPs para el tratamiento de úlceras crónicas de diferentes orígenes. 2019-01-20 2021-06-03T03:52:32Z 2021-06-03T03:52:32Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Research article Articulo de Investigación https://recit.uabc.mx/index.php/revista/article/view/oba8 10.37636/recit.v212025 https://hdl.handle.net/20.500.12930/7012 eng https://recit.uabc.mx/index.php/revista/article/view/oba8/20-25 https://recit.uabc.mx/index.php/revista/article/view/oba8/html https://recit.uabc.mx/index.php/revista/article/view/oba8/OBA8 Copyright (c) 2019 Almonaci Hernández Cesar Alejandro, Cabrera Torres Isis Marion, López-Acevedo Rosangela, Juárez-Moreno Karla Oyuki, Castañeda-Juárez Martin E., Almanza-Reyes Horacio, Pestryakov Alexey, Bogdanchikova Nina http://creativecommons.org/licenses/by/4.0 application/pdf text/html application/xml Universidad Autónoma de Baja California REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 2 No. 1 (2019); 20-25 REVISTA DE CIENCIAS TECNOLÓGICAS; Vol. 2 Núm. 1 (2019); 20-25 2594-1925
institution	Repositorio Institucional
collection	DSpace
language	eng
topic	Diabetic Foot Ulcers Diabetes Mellitus Silver Nanoparticles Nanomedicine Chronic Ulcers. Red Internacional de Bionanotecnología
spellingShingle	Diabetic Foot Ulcers Diabetes Mellitus Silver Nanoparticles Nanomedicine Chronic Ulcers. Red Internacional de Bionanotecnología Almonaci Hernández, Cesar Alejandro Cabrera Torres, Isis Marion López-Acevedo, Rosangela Juárez-Moreno, Karla Oyuki Castañeda-Juárez, Martin E. Almanza-Reyes, Horacio Pestryakov, Alexey Bogdanchikova, Nina Diabetic foot ulcers treatment with silver nanoparticles
description	Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedicine. Herein, we present the usage of AgNPs for the treatment of diabetic foot ulcers with a stage II in Wagner classification. In addition to conventional antibiotic treatment, the ulcers were treated with topical administration of AgNPs at a concentration of 1.2 mg/ml of metallic silver. The results showed a significant improvement in the evolution of the ulcers, where the edges of the lesion were effectively approached, granulation tissue being observed, edema decreased and fibrin plaques. These results form the basis for further studies on the use of AgNPs for the treatment of chronic ulcers of different origins.
format	info:eu-repo/semantics/article
author	Almonaci Hernández, Cesar Alejandro Cabrera Torres, Isis Marion López-Acevedo, Rosangela Juárez-Moreno, Karla Oyuki Castañeda-Juárez, Martin E. Almanza-Reyes, Horacio Pestryakov, Alexey Bogdanchikova, Nina
author_facet	Almonaci Hernández, Cesar Alejandro Cabrera Torres, Isis Marion López-Acevedo, Rosangela Juárez-Moreno, Karla Oyuki Castañeda-Juárez, Martin E. Almanza-Reyes, Horacio Pestryakov, Alexey Bogdanchikova, Nina
author_sort	Almonaci Hernández, Cesar Alejandro
title	Diabetic foot ulcers treatment with silver nanoparticles
title_short	Diabetic foot ulcers treatment with silver nanoparticles
title_full	Diabetic foot ulcers treatment with silver nanoparticles
title_fullStr	Diabetic foot ulcers treatment with silver nanoparticles
title_full_unstemmed	Diabetic foot ulcers treatment with silver nanoparticles
title_sort	diabetic foot ulcers treatment with silver nanoparticles
publisher	Universidad Autónoma de Baja California
publishDate	2019
url	https://recit.uabc.mx/index.php/revista/article/view/oba8
_version_	1792608724643217408

Diabetic foot ulcers treatment with silver nanoparticles

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